Motif ID: HOX{A6,A7,B6,B7}.p2

Z-value: 1.085


Transcription factors associated with HOX{A6,A7,B6,B7}.p2:

Gene SymbolEntrez IDGene Name
HOXA6 3203 homeobox A6
HOXA7 3204 homeobox A7
HOXB6 3216 homeobox B6
HOXB7 3217 homeobox B7

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
HOXA6chr7_-_27187367-0.462.5e-01Click!
HOXB7chr17_-_46687925-0.363.8e-01Click!
HOXA7chr7_-_271961630.275.2e-01Click!
HOXB6chr17_-_46682333-0.275.2e-01Click!


Activity profile for motif HOX{A6,A7,B6,B7}.p2.

activity profile for motif HOX{A6,A7,B6,B7}.p2


Sorted Z-values histogram for motif HOX{A6,A7,B6,B7}.p2

Sorted Z-values for motif HOX{A6,A7,B6,B7}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HOX{A6,A7,B6,B7}.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_-_31352489 1.537 NM_001253827
GALNT14
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr7_-_83824216 1.533 NM_006080
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr2_+_177016112 1.077 NM_014621
HOXD4
homeobox D4
chr12_+_41831484 1.002 NM_013377
PDZRN4
PDZ domain containing ring finger 4
chr18_+_61554938 0.999 NM_001143818
NM_002575
SERPINB2

serpin peptidase inhibitor, clade B (ovalbumin), member 2

chr12_-_71031174 0.966 NM_001109754
PTPRB
protein tyrosine phosphatase, receptor type, B
chr2_-_161056573 0.940 NM_000888
ITGB6
integrin, beta 6
chr11_-_115088628 0.936 CADM1
cell adhesion molecule 1
chr2_+_177016337 0.911


chr2_-_161056762 0.895 ITGB6
integrin, beta 6
chr12_-_105322056 0.844 NM_032148
SLC41A2
solute carrier family 41, member 2
chr7_-_41742666 0.779 NM_002192
INHBA
inhibin, beta A
chr13_-_103719195 0.773 NM_000452
SLC10A2
solute carrier family 10 (sodium/bile acid cotransporter family), member 2
chr8_+_104831415 0.753 NM_014677
RIMS2
regulating synaptic membrane exocytosis 2
chr3_+_130569368 0.745 NM_001199180
NM_001199181
NM_001199182
ATP2C1


ATPase, Ca++ transporting, type 2C, member 1


chr12_-_28124915 0.742 NM_002820
NM_198965
PTHLH

parathyroid hormone-like hormone

chr17_-_39093671 0.729 NM_015515
KRT23
keratin 23 (histone deacetylase inducible)
chr11_+_20620945 0.718 NM_004211
SLC6A5
solute carrier family 6 (neurotransmitter transporter, glycine), member 5
chr8_-_122653493 0.705 NM_005328
HAS2
hyaluronan synthase 2
chr5_-_24645084 0.698 NM_006727
CDH10
cadherin 10, type 2 (T2-cadherin)
chr11_-_124190092 0.695 NM_001002918
OR8D2
olfactory receptor, family 8, subfamily D, member 2
chr11_+_113775517 0.685 NM_006028
HTR3B
5-hydroxytryptamine (serotonin) receptor 3B
chr4_-_41884568 0.683


chr17_-_46651809 0.670 NM_002146
HOXB3
homeobox B3
chrM_+_9217 0.664


chr4_+_71494460 0.642 NM_031889
ENAM
enamelin
chr8_-_142264157 0.622 SLC45A4
solute carrier family 45, member 4
chr14_-_35344852 0.582 NM_013448
NM_182648
BAZ1A

bromodomain adjacent to zinc finger domain, 1A

chrM_+_9182 0.581


chr13_-_86373328 0.578 NM_032229
SLITRK6
SLIT and NTRK-like family, member 6
chr5_-_1882764 0.577 NM_016358
IRX4
iroquois homeobox 4
chr15_-_90347534 0.569 ANPEP
alanyl (membrane) aminopeptidase
chr5_+_166711842 0.567 NM_001122679
ODZ2
odz, odd Oz/ten-m homolog 2 (Drosophila)
chr3_-_79817058 0.564 NM_002941
ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr2_+_162272892 0.561 TBR1
T-box, brain, 1
chrM_+_8857 0.560


chr4_+_113970784 0.554 NM_001148
NM_020977
ANK2

ankyrin 2, neuronal

chr2_-_165424993 0.546 GRB14
growth factor receptor-bound protein 14
chr1_+_81771844 0.546 LPHN2
latrophilin 2
chr12_+_105153258 0.521 CHST11
carbohydrate (chondroitin 4) sulfotransferase 11
chr14_-_95599794 0.504 NM_001195573
DICER1
dicer 1, ribonuclease type III
chr10_+_118083939 0.503 NM_198515
C10orf96
chromosome 10 open reading frame 96
chr1_-_242612757 0.497 NM_001195811
NM_001195812
PLD5

phospholipase D family, member 5

chr18_+_29027731 0.496 NM_001944
DSG3
desmoglein 3
chr11_-_16424391 0.495 NM_001145819
NM_017508
SOX6

SRY (sex determining region Y)-box 6

chr9_-_117568292 0.495 NM_005118
TNFSF15
tumor necrosis factor (ligand) superfamily, member 15
chr9_-_8733893 0.474 NM_001040712
NM_001171025
NM_130391
NM_130392
NM_130393
PTPRD




protein tyrosine phosphatase, receptor type, D




chr8_-_93107643 0.470 RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr5_+_126984712 0.469 NM_001048252
CTXN3
cortexin 3
chrX_-_19817854 0.463 SH3KBP1
SH3-domain kinase binding protein 1
chr4_-_41750936 0.460 NM_003924
PHOX2B
paired-like homeobox 2b
chr18_-_53089722 0.458 NM_001243233
TCF4
transcription factor 4
chr2_-_215896809 0.457 NM_015657
ABCA12
ATP-binding cassette, sub-family A (ABC1), member 12
chr7_-_107880492 0.446 NM_001037132
NRCAM
neuronal cell adhesion molecule
chr2_-_216003068 0.444 NM_173076
ABCA12
ATP-binding cassette, sub-family A (ABC1), member 12
chrX_-_118726852 0.441 NM_001173488
NKRF
NFKB repressing factor
chr10_-_65028825 0.439 NM_004241
JMJD1C
jumonji domain containing 1C
chr17_-_39675078 0.436 NM_002275
KRT15
keratin 15
chr3_-_33700932 0.435 NM_001207044
CLASP2
cytoplasmic linker associated protein 2
chr17_-_49124128 0.431 NM_001251971
SPAG9
sperm associated antigen 9
chr2_-_166060552 0.431 NM_001081676
NM_001081677
NM_006922
SCN3A


sodium channel, voltage-gated, type III, alpha subunit


chr5_+_36606667 0.428 SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr17_-_39538635 0.424 NM_021013
KRT34
keratin 34
chr17_-_39092714 0.422 KRT23
keratin 23 (histone deacetylase inducible)
chr11_-_71752099 0.422 NUMA1
nuclear mitotic apparatus protein 1
chrM_+_10704 0.418


chr6_-_87804773 0.417 NM_000735
NM_001252383
CGA

glycoprotein hormones, alpha polypeptide

chr20_+_62795773 0.417 MYT1
myelin transcription factor 1
chr12_-_123187842 0.414 NM_177551
HCAR2
hydroxycarboxylic acid receptor 2
chr2_+_102508377 0.412 MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr17_-_64225496 0.410 NM_000042
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr4_+_69313166 0.409 NM_014058
TMPRSS11E
transmembrane protease, serine 11E
chr17_-_38911524 0.409 NM_181534
KRT25
keratin 25
chrX_-_19817907 0.408 NM_001024666
SH3KBP1
SH3-domain kinase binding protein 1
chr11_-_57195052 0.408 NM_017611
SLC43A3
solute carrier family 43, member 3
chr2_-_55237255 0.407 NM_007008
RTN4
reticulon 4
chr12_-_123201319 0.406 NM_006018
HCAR3
hydroxycarboxylic acid receptor 3
chr6_-_75965845 0.406 TMEM30A
transmembrane protein 30A
chr7_+_107110501 0.402 NM_005295
GPR22
G protein-coupled receptor 22
chr21_+_25801042 0.401 FLJ42200
FLJ42200 protein
chrM_+_6138 0.399


chr7_-_92855780 0.399 NM_001039372
HEPACAM2
HEPACAM family member 2
chrM_+_9725 0.395


chr10_+_115312777 0.393 NM_004132
HABP2
hyaluronan binding protein 2
chr5_+_36606456 0.392 NM_001166696
NM_004172
SLC1A3

solute carrier family 1 (glial high affinity glutamate transporter), member 3

chr8_-_93107442 0.389 NM_001198629
NM_001198630
NM_001198632
NM_175635
RUNX1T1



runt-related transcription factor 1; translocated to, 1 (cyclin D-related)



chr1_-_59147727 0.388


chr3_-_54961961 0.387 NM_020678
LRTM1
leucine-rich repeats and transmembrane domains 1
chr20_-_50418946 0.384 NM_020436
SALL4
sal-like 4 (Drosophila)
chr6_+_50681256 0.381 NM_172238
TFAP2D
transcription factor AP-2 delta (activating enhancer binding protein 2 delta)
chr10_+_118187381 0.381 NM_001011709
PNLIPRP3
pancreatic lipase-related protein 3
chr13_-_36050758 0.379 NM_005584
MAB21L1
mab-21-like 1 (C. elegans)
chr5_+_131409484 0.378 NM_000758
CSF2
colony stimulating factor 2 (granulocyte-macrophage)
chr5_+_147582338 0.378 NM_001195290
NM_205841
SPINK6

serine peptidase inhibitor, Kazal type 6

chr1_+_160160284 0.371 NM_001231
CASQ1
calsequestrin 1 (fast-twitch, skeletal muscle)
chr4_-_83347778 0.370 HNRPDL
heterogeneous nuclear ribonucleoprotein D-like
chrX_+_139791923 0.365 RP1-177G6.2
uncharacterized LOC286411
chrX_-_18690187 0.364 NM_000330
RS1
retinoschisin 1
chr1_+_179965756 0.359 CEP350
centrosomal protein 350kDa
chr17_-_46608271 0.358 NM_002144
HOXB1
homeobox B1
chr12_-_52946734 0.353 NM_033448
KRT71
keratin 71
chr12_-_24103953 0.349 SOX5
SRY (sex determining region Y)-box 5
chr4_+_30722445 0.349 PCDH7
protocadherin 7
chr3_-_55515361 0.347 WNT5A
wingless-type MMTV integration site family, member 5A
chr12_+_50869531 0.346 LARP4
La ribonucleoprotein domain family, member 4
chr2_+_102508333 0.345 MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chrM_+_10361 0.338


chr4_-_83347222 0.338 HNRPDL
heterogeneous nuclear ribonucleoprotein D-like
chr17_-_35656691 0.337 NM_198837
NM_198838
ACACA

acetyl-CoA carboxylase alpha

chr8_-_42234562 0.334 NM_014420
DKK4
dickkopf homolog 4 (Xenopus laevis)
chr4_+_55095263 0.329 NM_006206
PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chr3_-_33700480 0.325 CLASP2
cytoplasmic linker associated protein 2
chr1_-_241799101 0.324 NM_001821
CHML
choroideremia-like (Rab escort protein 2)
chr2_-_29297126 0.322 NM_001029883
C2orf71
chromosome 2 open reading frame 71
chr8_+_32579350 0.317 NM_001159996
NRG1
neuregulin 1
chr4_+_108814419 0.316 NM_001136257
NM_152621
SGMS2

sphingomyelin synthase 2

chrM_+_8364 0.314


chr16_-_51185150 0.314 NM_002968
SALL1
sal-like 1 (Drosophila)
chr8_+_98703361 0.313 MTDH
metadherin
chr14_-_35344450 0.312 BAZ1A
bromodomain adjacent to zinc finger domain, 1A
chr6_-_138820578 0.309 NM_001144060
NHSL1
NHS-like 1
chr7_+_48211054 0.308 NM_152701
ABCA13
ATP-binding cassette, sub-family A (ABC1), member 13
chr4_+_88754120 0.308 NM_001184695
NM_001184696
NM_001184697
NM_020203
MEPE



matrix extracellular phosphoglycoprotein



chr21_+_39628869 0.308 NM_170736
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr3_-_149095458 0.307 TM4SF1
transmembrane 4 L six family member 1
chr22_-_41257998 0.307 NM_145174
DNAJB7
DnaJ (Hsp40) homolog, subfamily B, member 7
chr4_+_113739203 0.306 NM_001127493
ANK2
ankyrin 2, neuronal
chr5_+_139876504 0.306 ANKHD1
ankyrin repeat and KH domain containing 1
chr4_-_139163222 0.306 NM_014331
SLC7A11
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr2_+_204801453 0.305 NM_012092
ICOS
inducible T-cell co-stimulator
chr3_-_149095517 0.304 NM_014220
TM4SF1
transmembrane 4 L six family member 1
chr18_-_30352841 0.304 NM_020805
KLHL14
kelch-like 14 (Drosophila)
chr1_-_217250230 0.304 NM_001243507
NM_001243509
ESRRG

estrogen-related receptor gamma

chr3_-_149095333 0.300 TM4SF1
transmembrane 4 L six family member 1
chr2_-_55199894 0.300


chr7_+_116660291 0.300 ST7
suppression of tumorigenicity 7
chr3_-_149095413 0.299 TM4SF1
transmembrane 4 L six family member 1
chr20_-_14318200 0.298 NM_013281
NM_198391
FLRT3

fibronectin leucine rich transmembrane protein 3

chr11_-_119599253 0.298 NM_002855
NM_203285
NM_203286
PVRL1


poliovirus receptor-related 1 (herpesvirus entry mediator C)


chr5_-_16509106 0.297 NM_019000
FAM134B
family with sequence similarity 134, member B
chr2_-_99871569 0.297 NM_175735
LYG2
lysozyme G-like 2
chr13_-_20805371 0.297 NM_006783
GJB6
gap junction protein, beta 6, 30kDa
chr14_-_54423448 0.296 NM_001202
NM_130850
BMP4

bone morphogenetic protein 4

chr6_+_83072922 0.295 NM_006670
TPBG
trophoblast glycoprotein
chr2_-_158300517 0.293 NM_004288
CYTIP
cytohesin 1 interacting protein
chr1_-_12677347 0.291 NM_004753
DHRS3
dehydrogenase/reductase (SDR family) member 3
chr1_+_186798031 0.290 NM_024420
PLA2G4A
phospholipase A2, group IVA (cytosolic, calcium-dependent)
chr4_+_114214102 0.290 ANK2
ankyrin 2, neuronal
chr2_+_54785453 0.290 NM_178313
SPTBN1
spectrin, beta, non-erythrocytic 1
chr1_+_159409511 0.288 NM_012351
OR10J1
olfactory receptor, family 10, subfamily J, member 1
chr4_+_39408472 0.285 NM_175737
KLB
klotho beta
chr4_+_71200670 0.284 NM_033122
CABS1
calcium-binding protein, spermatid-specific 1
chr6_-_53013581 0.284 NM_003643
GCM1
glial cells missing homolog 1 (Drosophila)
chr2_+_171571800 0.284 NM_001003845
SP5
Sp5 transcription factor
chr6_-_119252887 0.283 NM_017696
MCM9
minichromosome maintenance complex component 9
chr14_+_70236266 0.282 SRSF5
serine/arginine-rich splicing factor 5
chr13_-_60325073 0.282


chr12_-_51422012 0.281 NM_001174125
SLC11A2
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr20_+_58630965 0.280 NM_173644
C20orf197
chromosome 20 open reading frame 197
chrX_-_49965003 0.278 NM_139289
AKAP4
A kinase (PRKA) anchor protein 4
chrM_+_3081 0.277


chr3_+_127641901 0.276 NM_207335
KBTBD12
kelch repeat and BTB (POZ) domain containing 12
chr17_-_38956146 0.275 NM_181535
KRT28
keratin 28
chrX_+_105937067 0.275 NM_024539
RNF128
ring finger protein 128
chr5_-_160279045 0.275 NM_025153
ATP10B
ATPase, class V, type 10B
chr4_+_41258895 0.275 NM_004181
UCHL1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr3_-_123339178 0.273 MYLK
myosin light chain kinase
chr21_-_27253197 0.272 APP
amyloid beta (A4) precursor protein
chr11_+_131240370 0.272 NM_001048209
NTM
neurotrimin
chr10_-_105845619 0.271 NM_000494
COL17A1
collagen, type XVII, alpha 1
chr9_+_127420690 0.270 MIR181A2HG
MIR181A2 host gene (non-protein coding)
chr2_+_109384601 0.270 RANBP2
RAN binding protein 2
chrM_+_10123 0.270


chr9_-_86584079 0.269 HNRNPK
heterogeneous nuclear ribonucleoprotein K
chr9_+_132083294 0.267 NM_001012715
C9orf106
chromosome 9 open reading frame 106
chr7_+_141478241 0.266 NM_016944
TAS2R4
taste receptor, type 2, member 4
chr7_+_114055234 0.266 FOXP2
forkhead box P2
chr17_-_67240955 0.266 NM_080282
ABCA10
ATP-binding cassette, sub-family A (ABC1), member 10
chr15_-_34610928 0.265 NM_005135
SLC12A6
solute carrier family 12 (potassium/chloride transporters), member 6
chr16_+_7382750 0.265 NM_145891
NM_145892
NM_145893
RBFOX1


RNA binding protein, fox-1 homolog (C. elegans) 1


chr6_+_47666288 0.265 NM_153838
GPR115
G protein-coupled receptor 115
chr3_+_1134619 0.264 NM_014461
CNTN6
contactin 6
chr7_-_126883568 0.263 NM_000845
GRM8
glutamate receptor, metabotropic 8
chr6_-_155777036 0.263 NM_015718
NOX3
NADPH oxidase 3
chr16_+_56817367 0.262 NM_001242796
NUP93
nucleoporin 93kDa
chr2_+_183608329 0.262 DNAJC10
DnaJ (Hsp40) homolog, subfamily C, member 10
chr14_-_35344490 0.262 BAZ1A
bromodomain adjacent to zinc finger domain, 1A
chr8_+_80523339 0.261 STMN2
stathmin-like 2
chr14_+_62462540 0.261 NM_031914
SYT16
synaptotagmin XVI
chrM_+_12283 0.260


chr6_+_121756744 0.260 NM_000165
GJA1
gap junction protein, alpha 1, 43kDa
chr1_-_168513201 0.260 NM_003175
XCL1
XCL2
chemokine (C motif) ligand 1
chemokine (C motif) ligand 2
chr14_-_35344526 0.260 BAZ1A
bromodomain adjacent to zinc finger domain, 1A
chr8_+_80523304 0.259 STMN2
stathmin-like 2
chr8_+_80523376 0.258 STMN2
stathmin-like 2
chr6_+_12290528 0.257 NM_001168319
NM_001955
EDN1

endothelin 1

chr3_-_155394104 0.257 NM_001130960
NM_001130961
PLCH1

phospholipase C, eta 1

chr11_+_87032428 0.257 TMEM135
transmembrane protein 135
chr9_-_117880411 0.257 NM_002160
TNC
tenascin C
chr2_-_38525527 0.256 ATL2
atlastin GTPase 2

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.37 4.40e-21 GO:0007275 multicellular organismal development
1.35 6.42e-21 GO:0032502 developmental process
1.41 4.43e-20 GO:0048731 system development
1.37 1.18e-18 GO:0048856 anatomical structure development
1.24 2.81e-14 GO:0032501 multicellular organismal process
1.51 7.87e-14 GO:0009653 anatomical structure morphogenesis
1.43 7.28e-13 GO:0048513 organ development
1.49 8.80e-13 GO:0007399 nervous system development
1.10 1.04e-11 GO:0009987 cellular process
1.39 1.14e-11 GO:0030154 cell differentiation
1.38 5.76e-11 GO:0048869 cellular developmental process
1.66 9.07e-11 GO:2000026 regulation of multicellular organismal development
1.60 1.11e-10 GO:0050793 regulation of developmental process
1.65 2.81e-10 GO:0010557 positive regulation of macromolecule biosynthetic process
1.66 1.61e-09 GO:0045595 regulation of cell differentiation
1.58 3.47e-09 GO:0009891 positive regulation of biosynthetic process
1.82 3.73e-09 GO:0051094 positive regulation of developmental process
1.68 3.93e-09 GO:0045893 positive regulation of transcription, DNA-dependent
1.57 6.95e-09 GO:0031328 positive regulation of cellular biosynthetic process
1.64 1.34e-08 GO:0010628 positive regulation of gene expression
1.63 4.00e-08 GO:0051254 positive regulation of RNA metabolic process
1.52 8.94e-08 GO:0022008 neurogenesis
1.30 9.16e-08 GO:0048522 positive regulation of cellular process
1.49 1.38e-07 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.57 1.56e-07 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.49 2.37e-07 GO:0042127 regulation of cell proliferation
1.70 2.44e-07 GO:0000904 cell morphogenesis involved in differentiation
1.52 2.46e-07 GO:0048699 generation of neurons
1.27 2.84e-07 GO:0048518 positive regulation of biological process
1.51 6.31e-07 GO:0009888 tissue development
1.54 7.51e-07 GO:0051173 positive regulation of nitrogen compound metabolic process
1.57 7.59e-07 GO:0030182 neuron differentiation
1.62 7.93e-07 GO:0000902 cell morphogenesis
1.72 1.08e-06 GO:0048812 neuron projection morphogenesis
1.82 1.85e-06 GO:0045597 positive regulation of cell differentiation
1.68 1.95e-06 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.71 2.93e-06 GO:0048667 cell morphogenesis involved in neuron differentiation
1.12 3.05e-06 GO:0065007 biological regulation
1.66 3.69e-06 GO:0031175 neuron projection development
1.39 5.00e-06 GO:0051239 regulation of multicellular organismal process
1.71 5.01e-06 GO:0007409 axonogenesis
1.64 6.10e-06 GO:0032990 cell part morphogenesis
1.64 6.47e-06 GO:0048858 cell projection morphogenesis
1.75 6.88e-06 GO:0043009 chordate embryonic development
1.41 7.65e-06 GO:0010604 positive regulation of macromolecule metabolic process
1.53 1.01e-05 GO:0009790 embryo development
1.28 1.14e-05 GO:0048523 negative regulation of cellular process
1.44 1.22e-05 GO:0009605 response to external stimulus
1.56 1.33e-05 GO:0032989 cellular component morphogenesis
1.73 1.40e-05 GO:0009792 embryo development ending in birth or egg hatching
1.13 1.92e-05 GO:0050794 regulation of cellular process
1.55 2.09e-05 GO:0030030 cell projection organization
1.38 2.14e-05 GO:0009893 positive regulation of metabolic process
2.68 3.29e-05 GO:0022612 gland morphogenesis
1.65 4.16e-05 GO:0032583 regulation of gene-specific transcription
1.56 4.84e-05 GO:0048666 neuron development
1.55 5.10e-05 GO:0009887 organ morphogenesis
1.82 5.57e-05 GO:0048545 response to steroid hormone stimulus
1.97 9.89e-05 GO:0048732 gland development
1.92 1.03e-04 GO:0043193 positive regulation of gene-specific transcription
1.44 1.10e-04 GO:0006351 transcription, DNA-dependent
1.42 1.11e-04 GO:0048468 cell development
1.60 1.12e-04 GO:0072358 cardiovascular system development
1.60 1.12e-04 GO:0072359 circulatory system development
1.47 1.40e-04 GO:0007155 cell adhesion
1.47 1.40e-04 GO:0022610 biological adhesion
1.36 1.91e-04 GO:0031325 positive regulation of cellular metabolic process
1.25 2.01e-04 GO:0048519 negative regulation of biological process
1.56 2.30e-04 GO:0008284 positive regulation of cell proliferation
1.11 6.68e-04 GO:0050789 regulation of biological process
1.68 6.90e-04 GO:0007411 axon guidance
2.06 8.08e-04 GO:0050678 regulation of epithelial cell proliferation
2.51 9.29e-04 GO:0048638 regulation of developmental growth
1.79 1.45e-03 GO:0003002 regionalization
1.36 1.71e-03 GO:0007154 cell communication
2.00 1.79e-03 GO:0045165 cell fate commitment
1.53 1.87e-03 GO:0007417 central nervous system development
1.40 1.94e-03 GO:0040011 locomotion
1.73 2.00e-03 GO:0001568 blood vessel development
2.37 2.02e-03 GO:0048706 embryonic skeletal system development
1.21 2.24e-03 GO:0071842 cellular component organization at cellular level
2.90 2.52e-03 GO:0051781 positive regulation of cell division
1.37 2.63e-03 GO:0032774 RNA biosynthetic process
1.66 2.78e-03 GO:0060284 regulation of cell development
2.63 2.83e-03 GO:0016202 regulation of striated muscle tissue development
1.23 2.93e-03 GO:0042221 response to chemical stimulus
1.17 3.76e-03 GO:0023052 signaling
1.34 4.27e-03 GO:0010646 regulation of cell communication
1.46 5.14e-03 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.67 5.58e-03 GO:0070848 response to growth factor stimulus
1.67 5.60e-03 GO:0001944 vasculature development
1.20 5.83e-03 GO:0071841 cellular component organization or biogenesis at cellular level
1.48 6.37e-03 GO:0045892 negative regulation of transcription, DNA-dependent
1.43 6.46e-03 GO:0009719 response to endogenous stimulus
2.54 6.53e-03 GO:0048634 regulation of muscle organ development
1.45 6.58e-03 GO:0051172 negative regulation of nitrogen compound metabolic process
1.48 6.91e-03 GO:0051253 negative regulation of RNA metabolic process
1.59 7.53e-03 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
1.45 8.50e-03 GO:0009725 response to hormone stimulus
1.88 1.12e-02 GO:0010552 positive regulation of gene-specific transcription from RNA polymerase II promoter
1.41 1.26e-02 GO:0009890 negative regulation of biosynthetic process
1.41 1.44e-02 GO:0031327 negative regulation of cellular biosynthetic process
1.63 1.57e-02 GO:0016337 cell-cell adhesion
1.54 1.58e-02 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.43 1.63e-02 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
2.49 1.68e-02 GO:0050680 negative regulation of epithelial cell proliferation
1.17 1.83e-02 GO:0016043 cellular component organization
1.47 1.95e-02 GO:0006935 chemotaxis
1.47 1.95e-02 GO:0042330 taxis
1.61 1.98e-02 GO:0022603 regulation of anatomical structure morphogenesis
1.41 2.04e-02 GO:0010558 negative regulation of macromolecule biosynthetic process
1.23 2.05e-02 GO:0010467 gene expression
1.21 2.29e-02 GO:0065008 regulation of biological quality
1.60 2.33e-02 GO:0001501 skeletal system development
1.43 2.62e-02 GO:0010629 negative regulation of gene expression
1.84 2.64e-02 GO:0009952 anterior/posterior pattern formation
1.16 2.65e-02 GO:0071840 cellular component organization or biogenesis
1.95 2.79e-02 GO:0001763 morphogenesis of a branching structure
1.90 3.52e-02 GO:0007156 homophilic cell adhesion
1.54 3.54e-02 GO:0007420 brain development
1.56 3.58e-02 GO:0007389 pattern specification process
1.19 4.04e-02 GO:0010556 regulation of macromolecule biosynthetic process
2.34 4.21e-02 GO:0030518 steroid hormone receptor signaling pathway
1.96 4.38e-02 GO:0033273 response to vitamin
1.32 4.43e-02 GO:0032879 regulation of localization
1.20 4.67e-02 GO:0051252 regulation of RNA metabolic process
2.28 4.84e-02 GO:0009953 dorsal/ventral pattern formation
1.53 4.86e-02 GO:0048598 embryonic morphogenesis

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.34 1.67e-10 GO:0044459 plasma membrane part
1.57 8.87e-07 GO:0030054 cell junction
1.59 1.30e-04 GO:0045202 synapse
1.36 1.51e-04 GO:0044421 extracellular region part
1.58 4.14e-04 GO:0009986 cell surface
1.15 5.32e-04 GO:0005886 plasma membrane
1.15 5.85e-04 GO:0071944 cell periphery
1.73 7.37e-04 GO:0016323 basolateral plasma membrane
1.61 1.24e-03 GO:0005578 proteinaceous extracellular matrix
1.80 2.14e-03 GO:0030424 axon
3.45 2.78e-03 GO:0045178 basal part of cell
1.51 8.42e-03 GO:0031012 extracellular matrix
2.39 8.56e-03 GO:0031091 platelet alpha granule
2.53 9.74e-03 GO:0031093 platelet alpha granule lumen
2.48 1.44e-02 GO:0034774 secretory granule lumen
2.40 1.76e-02 GO:0031983 vesicle lumen
1.91 1.92e-02 GO:0044420 extracellular matrix part
1.31 2.13e-02 GO:0042995 cell projection
2.38 3.03e-02 GO:0060205 cytoplasmic membrane-bounded vesicle lumen
1.45 3.60e-02 GO:0043005 neuron projection
1.24 3.95e-02 GO:0031226 intrinsic to plasma membrane
1.19 4.49e-02 GO:0005576 extracellular region
1.31 4.94e-02 GO:0005615 extracellular space

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.61 5.05e-09 GO:0043565 sequence-specific DNA binding
1.45 2.00e-07 GO:0030528 transcription regulator activity
1.45 5.91e-07 GO:0001071 nucleic acid binding transcription factor activity
1.45 5.91e-07 GO:0003700 sequence-specific DNA binding transcription factor activity
1.42 2.97e-06 GO:0005102 receptor binding
1.12 8.58e-06 GO:0005515 protein binding
1.88 7.38e-05 GO:0000975 regulatory region DNA binding
1.88 7.38e-05 GO:0001067 regulatory region nucleic acid binding
1.88 7.38e-05 GO:0044212 transcription regulatory region DNA binding
1.90 7.49e-05 GO:0010843 promoter binding
1.46 1.60e-04 GO:0005509 calcium ion binding
1.82 7.54e-03 GO:0008083 growth factor activity
2.37 2.49e-02 GO:0042562 hormone binding
2.40 3.00e-02 GO:0051015 actin filament binding
1.53 3.18e-02 GO:0016563 transcription activator activity
1.48 3.93e-02 GO:0000988 protein binding transcription factor activity
1.48 3.93e-02 GO:0000989 transcription factor binding transcription factor activity
1.77 4.13e-02 GO:0046873 metal ion transmembrane transporter activity
1.68 4.64e-02 GO:0003682 chromatin binding